Sdhb conditional Knockout mouse

Target

Gene symbol :

Sdhb

NCBI gene ID :

67680

Gene full name :

Succinate dehydrogenase complex iron sulfur subunit B

Synonym :

SDH2, Sdhb1

Protein function

Protein name :

SDHB protein (mitochondrial)

Component of mitochondrial complex II; involved in Krebs cycle and ETC

Expected phenotype

Mitochondrial dysfunction

Human disease relevance

Associated with paragangliomas, Leigh syndrome

Model applications

Mitochondrial disease, cancer metabolism

Keywords:

Mitochondria, Krebs cycle, Complex II

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Sdhb

conditional Knockout mouse

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