Smc3 conditional Knockout mouse

Target

Gene symbol :

Smc3

NCBI gene ID :

13006

Gene full name :

Structural maintenance of chromosomes 3

Synonym :

Structural maintenance of chromosomes 3

Protein function

Protein name :

SMC3

Component of the cohesin complex essential for chromosome segregation.

Expected phenotype

Embryonic lethality, genomic instability

Human disease relevance

Involved in Cornelia de Lange syndrome

Model applications

Cohesin biology, chromosome cohesion

Keywords:

Cohesin, Cell cycle, Genome stability

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Smc3

conditional Knockout mouse

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