Target

Gene symbol :  
Sms
NCBI gene ID :  
20603
Gene full name :  
Spermine synthase
Synonym :  
Spermine synthase

Protein function

Protein name :  
SMS
Enzyme converting spermidine to spermine; critical for polyamine metabolism

Expected phenotype

Growth defects, altered spermatogenesis

Human disease relevance

Associated with Snyder-Robinson syndrome

Model applications

Models for metabolic and developmental disorders

Keywords:

Polyamine metabolism, Growth, Fertility

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Sms

conditional Knockout mouse

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