Target

Gene symbol :  
Uhrf1
NCBI gene ID :  
18140
Gene full name :  
Ubiquitin-like with PHD and RING finger domains 1
Synonym :  
ICBP90, Np95

Protein function

Protein name :  
UHRF1
Epigenetic regulator; links DNA methylation and histone modification.

Expected phenotype

Aberrant DNA methylation; developmental defects.

Human disease relevance

Associated with cancer and epigenetic disorders.

Model applications

Studies on epigenetic regulation and gene silencing.

Keywords:

Epigenetics, DNA methylation, Histone modification

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Uhrf1

conditional Knockout mouse

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