Usp42 conditional Knockout mouse

Target

Gene symbol :

Usp42

NCBI gene ID :

76800

Gene full name :

Ubiquitin specific peptidase 42

Synonym :

—

Protein function

Protein name :

Ubiquitin carboxyl-terminal hydrolase 42

Deubiquitinase that regulates p53 stability and transcriptional activity

Expected phenotype

Knockouts show altered cell cycle and p53 response

Human disease relevance

Involved in tumor suppression and stress response via p53 pathway

Model applications

Studied in deubiquitination, p53 signaling, and cell cycle control

Keywords:

Deubiquitinase, p53, Ubiquitin, Tumor suppression

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Usp42

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe