Target

Gene symbol :  
Amer1
NCBI gene ID :  
72345
Gene full name :  
APC membrane recruitment 1
Synonym :  
WTX, FAM123B

Protein function

Protein name :  
AMER1
Negative regulator of Wnt signaling; involved in cell growth control.

Expected phenotype

Abnormal development, tumor suppression

Human disease relevance

Linked to Wilms tumor and bone dysplasia

Model applications

Wnt signaling, cancer suppression

Keywords:

WTX, Wnt, Tumor suppressor

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Amer1

conditional Knockout mouse

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