Amer1 conditional Knockout mouse

Target

Gene symbol :

Amer1

NCBI gene ID :

72345

Gene full name :

APC membrane recruitment 1

Synonym :

WTX, FAM123B

Protein function

Protein name :

AMER1

Negative regulator of Wnt signaling; involved in cell growth control.

Expected phenotype

Abnormal development, tumor suppression

Human disease relevance

Linked to Wilms tumor and bone dysplasia

Model applications

Wnt signaling, cancer suppression

Keywords:

WTX, Wnt, Tumor suppressor

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Amer1

conditional Knockout mouse

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