Atxn2 conditional Knockout mouse

Target

Gene symbol :

Atxn2

NCBI gene ID :

20239

Gene full name :

Ataxin 2

Synonym :

Ataxin-2, Spinocerebellar ataxia 2

Protein function

Protein name :

Ataxin-2

RNA-binding protein regulating translation and stress granules; modulates TDP-43 toxicity.

Expected phenotype

Neurodegeneration, motor defects

Human disease relevance

Implicated in spinocerebellar ataxia 2 (SCA2), ALS

Model applications

Neurodegeneration, RNA metabolism, motor neuron disease

Keywords:

SCA2, TDP-43, RNA granules, ALS

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
WoldWide delivery by professional breeders

Atxn2

conditional Knockout mouse

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hPD-1 hLAG3

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hPD-1 hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1 hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1 hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.