Hnf4a conditional Knockout mouse

Target

Gene symbol :

Hnf4a

NCBI gene ID :

15378

Gene full name :

Hepatocyte nuclear factor 4 alpha

Synonym :

HNF-4alpha, MODY1, NR2A1

Protein function

Protein name :

HNF4A

Nuclear receptor that regulates gene expression in liver and pancreas.

Expected phenotype

Metabolic dysregulation

Human disease relevance

Mutations cause maturity-onset diabetes of the young (MODY1).

Model applications

Models for diabetes and metabolic disorders.

Keywords:

Transcription Factor, Diabetes, Metabolism

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Hnf4a

conditional Knockout mouse

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