Hnf4a conditional Knockout mouse

Target

Gene symbol :

Hnf4a

NCBI gene ID :

15378

Gene full name :

Hepatocyte nuclear factor 4 alpha

Synonym :

HNF-4alpha, MODY1, NR2A1

Protein function

Protein name :

HNF4A

Nuclear receptor that regulates gene expression in liver and pancreas.

Expected phenotype

Metabolic dysregulation

Human disease relevance

Mutations cause maturity-onset diabetes of the young (MODY1).

Model applications

Models for diabetes and metabolic disorders.

Keywords:

Transcription Factor, Diabetes, Metabolism

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Hnf4a

conditional Knockout mouse

Get in touch about

Let us know how we can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe