Target

Gene symbol :  
Mettl3
NCBI gene ID :  
56335
Gene full name :  
Methyltransferase like 3
Synonym :  
M6A methyltransferase

Protein function

Protein name :  
METTL3
Catalytic core of m6A methyltransferase complex; regulates mRNA stability and splicing.

Expected phenotype

Altered RNA metabolism, embryonic lethality

Human disease relevance

Essential in cancer, development, and stem cell biology

Model applications

Epitranscriptomics, gene expression regulation

Keywords:

m6A, RNA methylation, Stem cell

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Mettl3

conditional Knockout mouse

Get in touch about

Let us know how can help
Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe