Target

Gene symbol :  
Mettl3
NCBI gene ID :  
56335
Gene full name :  
Methyltransferase like 3
Synonym :  
M6A methyltransferase

Protein function

Protein name :  
METTL3
Catalytic core of m6A methyltransferase complex; regulates mRNA stability and splicing.

Expected phenotype

Altered RNA metabolism, embryonic lethality

Human disease relevance

Essential in cancer, development, and stem cell biology

Model applications

Epitranscriptomics, gene expression regulation

Keywords:

m6A, RNA methylation, Stem cell

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Mettl3

conditional Knockout mouse

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