Mmp12 conditional Knockout mouse

Target

Gene symbol :

Mmp12

NCBI gene ID :

17381

Gene full name :

Matrix metallopeptidase 12

Synonym :

MME, ME, Macrophage elastase

Protein function

Protein name :

MMP12

Metalloproteinase involved in extracellular matrix remodeling and tissue repair.

Expected phenotype

Impaired tissue remodeling and inflammatory responses

Human disease relevance

Associated with chronic obstructive pulmonary disease and atherosclerosis.

Model applications

Studies on tissue remodeling and inflammatory diseases.

Keywords:

Metalloproteinase, Tissue remodeling, Inflammation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Mmp12

conditional Knockout mouse

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