Target

Gene symbol :  
Mmp12
NCBI gene ID :  
17381
Gene full name :  
Matrix metallopeptidase 12
Synonym :  
MME, ME, Macrophage elastase

Protein function

Protein name :  
MMP12
Metalloproteinase involved in extracellular matrix remodeling and tissue repair.

Expected phenotype

Impaired tissue remodeling and inflammatory responses

Human disease relevance

Associated with chronic obstructive pulmonary disease and atherosclerosis.

Model applications

Studies on tissue remodeling and inflammatory diseases.

Keywords:

Metalloproteinase, Tissue remodeling, Inflammation

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • WoldWide delivery by professional breeders

Mmp12

conditional Knockout mouse

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