Npc1 conditional Knockout mouse

Target

Gene symbol :

Npc1

NCBI gene ID :

18145

Gene full name :

NPC intracellular cholesterol transporter 1

Synonym :

Niemann-Pick disease, type C1

Protein function

Protein name :

NPC1

Mediates intracellular cholesterol trafficking; essential for lipid homeostasis.

Expected phenotype

Cholesterol accumulation; neurodegeneration.

Human disease relevance

Causes Niemann-Pick disease type C1.

Model applications

Models for lipid storage disorders and neurodegeneration.

Keywords:

Cholesterol transport, Lysosomal storage, Neurodegeneration

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
WoldWide delivery by professional breeders

Npc1

conditional Knockout mouse

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hPD-1 hLAG3

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hPD-1 hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1 hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1 hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.