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A4GALT encodes alpha 1,4-galactosyltransferase, an enzyme involved in glycosphingolipid biosynthesis and cell surface antigen formation. Its expression is associated with epithelial tissues and cellular processes related to membrane composition and glycosylation. The A4galt-CreERT2 mouse line enables inducible, temporal control of genetic recombination in A4galt-expressing cells following tamoxifen administration. This model is suitable for studying glycosylation pathways, membrane biology, and epithelial tissue function.
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