Cfap126-CreERT2 mouse line

Inducible Cre driver for ciliated and Cfap126-expressing cells

Availability & Delivery:

• Cryo-recovery using in-house SOPF facilities • Worldwide delivery by professional breeders

Specifications

Expression driver gene:
Cfap126
Target system:
Ciliated cells, reproductive and epithelial tissues
Genetic background:
C57BL/6N
Cre type:
Inducible CreERT2
Reporter:
EGFP
Induction method:
Tamoxifen administration
MGI ID:
MGI:5659541

Scientific relevance & applications  

CFAP126 (cilia and flagella associated protein 126) is associated with ciliary structure and function, with expression reported in tissues containing motile cilia such as reproductive and epithelial systems. Proteins involved in ciliary function are critical for cellular motility and signaling. The Cfap126-CreERT2 mouse line enables inducible, temporal control of genetic recombination in Cfap126-expressing cells following tamoxifen administration. This model is suitable for studying cilia biology, epithelial function, and related developmental processes.

Cfap126-CreERT2 mouse line

mouse line

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