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CRISP3 encodes cysteine-rich secretory protein 3, which is expressed in glandular and epithelial tissues, including salivary glands and other secretory organs. It is associated with immune modulation and epithelial function. The Crisp3-CreERT2 mouse line enables inducible, temporal control of genetic recombination in Crisp3-expressing cells following tamoxifen administration. This model is suitable for studying epithelial biology, glandular function, and secretory processes.
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