Crisp3-CreERT2 mouse line

Inducible Cre driver for epithelial and secretory Crisp3-expressing cells

Availability & Delivery:

• Cryo-recovery using in-house SOPF facilities • Worldwide delivery by professional breeders

Specifications

Expression driver gene:
Crisp3
Target system:
Epithelial tissues, glandular system
Genetic background:
C57BL/6N
Cre type:
Inducible CreERT2
Reporter:
EGFP
Induction method:
Tamoxifen administration
MGI ID:
MGI:6122926

Scientific relevance & applications  

CRISP3 encodes cysteine-rich secretory protein 3, which is expressed in glandular and epithelial tissues, including salivary glands and other secretory organs. It is associated with immune modulation and epithelial function. The Crisp3-CreERT2 mouse line enables inducible, temporal control of genetic recombination in Crisp3-expressing cells following tamoxifen administration. This model is suitable for studying epithelial biology, glandular function, and secretory processes.

Crisp3-CreERT2 mouse line

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