Cryga-CreERT2 mouse line

Inducible Cre driver for lens-specific Cryga-expressing cells

Availability & Delivery:

• Cryo-recovery using in-house SOPF facilities • Worldwide delivery by professional breeders

Specifications

Expression driver gene:
Cryga
Target system:
Eye, lens
Genetic background:
C57BL/6N
Cre type:
Inducible CreERT2
Reporter:
EGFP
Induction method:
Tamoxifen administration
MGI ID:
MGI:6122917

Scientific relevance & applications  

CRYGA encodes gamma-crystallin A, a structural protein of the eye lens essential for maintaining transparency and refractive properties. Its expression is highly restricted to lens fiber cells. The Cryga-CreERT2 mouse line enables inducible, temporal control of genetic recombination in Cryga-expressing lens cells following tamoxifen administration. This model is particularly suited for studying lens development, transparency, and cataract formation.

Cryga-CreERT2 mouse line

mouse line

Get in touch about

Let us know how we can help
Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe