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CSK encodes C-terminal Src kinase, a key regulator of Src family kinases involved in intracellular signaling pathways across multiple cell types. Its expression is broadly distributed and plays roles in immune signaling, cell proliferation, and cellular homeostasis. The Csk-CreERT2 mouse line enables inducible, temporal control of genetic recombination in Csk-expressing cells following tamoxifen administration. This model is suitable for studying signaling pathways, kinase regulation, and cell-type-specific responses in diverse biological contexts.
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