Dmbx1-CreERT2 mouse line

Inducible Cre driver for neuronal Dmbx1-expressing cells

Availability & Delivery:

• Cryo-recovery using in-house SOPF facilities • Worldwide delivery by professional breeders

Specifications

Expression driver gene:
Dmbx1
Target system:
Nervous system
Genetic background:
C57BL/6N
Cre type:
Inducible CreERT2
Reporter:
EGFP
Induction method:
Tamoxifen administration
MGI ID:
MGI:5659567

Scientific relevance & applications  

DMBX1 is a homeobox transcription factor involved in brain development and neuronal differentiation. It is primarily expressed in specific regions of the developing and adult central nervous system, where it contributes to neural patterning and cell fate specification. The Dmbx1-CreERT2 mouse line enables inducible, temporal control of genetic recombination in Dmbx1-expressing neuronal populations following tamoxifen administration. This model is suitable for studying gene function in neurodevelopment, neuronal differentiation, and central nervous system biology.

Dmbx1-CreERT2 mouse line

mouse line

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