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• Cryo-recovery using in-house SOPF facilities • Worldwide delivery by professional breeders
GCHFR encodes GTP cyclohydrolase I feedback regulator, a key modulator of tetrahydrobiopterin (BH4) synthesis, which is essential for neurotransmitter production and nitric oxide signaling. Its expression is linked to metabolic and signaling pathways across multiple tissues. The Gchfr-CreERT2 mouse line enables inducible, temporal control of genetic recombination in Gchfr-expressing cells following tamoxifen administration. This model is suitable for studying metabolic regulation, neurotransmitter synthesis, and signaling pathways.
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Models with certified health status from professional breeders in US and Europe
