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GNG4 encodes a gamma subunit of heterotrimeric G proteins involved in intracellular signaling pathways, with enriched expression in specific neuronal populations. It plays a role in signal transduction and neuronal communication. The Gng4-CreERT2 mouse line enables inducible, temporal control of genetic recombination in Gng4-expressing neuronal cells following tamoxifen administration. This model is suitable for studying neuronal signaling, circuit function, and brain physiology.
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