Gng4-CreERT2 mouse line

Inducible Cre driver for neuronal Gng4-expressing cells

Availability & Delivery:

• Cryo-recovery using in-house SOPF facilities • Worldwide delivery by professional breeders

Specifications

Expression driver gene:
Gng4
Target system:
Nervous system
Genetic background:
C57BL/6N
Cre type:
Inducible CreERT2
Reporter:
EGFP
Induction method:
Tamoxifen administration
MGI ID:
MGI:6122929

Scientific relevance & applications  

GNG4 encodes a gamma subunit of heterotrimeric G proteins involved in intracellular signaling pathways, with enriched expression in specific neuronal populations. It plays a role in signal transduction and neuronal communication. The Gng4-CreERT2 mouse line enables inducible, temporal control of genetic recombination in Gng4-expressing neuronal cells following tamoxifen administration. This model is suitable for studying neuronal signaling, circuit function, and brain physiology.

Gng4-CreERT2 mouse line

mouse line

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