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• Cryo-recovery using in-house SOPF facilities • Worldwide delivery by professional breeders
HDC encodes histidine decarboxylase, the enzyme responsible for histamine synthesis. It is expressed in histaminergic neurons and immune cells such as mast cells, where it plays a central role in neurotransmission and inflammatory responses. The Hdc-CreERT2 mouse line enables inducible, temporal control of genetic recombination in Hdc-expressing cells following tamoxifen administration. This model is suitable for studying histamine signaling, neuroimmune interactions, and inflammatory diseases.
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Models with certified health status from professional breeders in US and Europe
