Krt82-CreERT2 mouse line

Inducible Cre driver for hair follicle and epithelial Krt82-expressing cells

Availability & Delivery:

• Cryo-recovery using in-house SOPF facilities • Worldwide delivery by professional breeders

Specifications

Expression driver gene:
Krt82
Target system:
Skin, hair follicles, epithelial tissues
Genetic background:
C57BL/6N
Cre type:
Inducible CreERT2
Reporter:
EGFP
Induction method:
Tamoxifen administration
MGI ID:
MGI:6122643

Scientific relevance & applications  

KRT82 encodes a type II hair keratin expressed in hair follicles, where it contributes to hair shaft formation and structural integrity. Its expression is highly specific to differentiated epithelial cells within the hair follicle. The Krt82-CreERT2 mouse line enables inducible, temporal control of genetic recombination in Krt82-expressing cells following tamoxifen administration. This model is well suited for studying hair biology, epithelial differentiation, and skin-related disorders.

Krt82-CreERT2 mouse line

mouse line

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