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• Cryo-recovery using in-house SOPF facilities • Worldwide delivery by professional breeders
LEF1 is a transcription factor mediating Wnt signaling, a pathway essential for embryonic development, stem cell maintenance, and tissue regeneration. It is expressed in multiple tissues, particularly during development and in proliferative cell populations. The Lef1-CreERT2 mouse line enables inducible, temporal control of genetic recombination in Lef1-expressing cells following tamoxifen administration. This model is suitable for studying Wnt signaling, development, and regenerative processes.
From model design to experimental results
Featured in 600+ scientific articles
Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions
Generated with biopharma partners and in-house
and guaranteed freedom to operate
Models with certified health status from professional breeders in US and Europe
