Myh7-CreERT2 mouse line

Inducible Cre driver for cardiac and slow-twitch muscle Myh7-expressing cells

Availability & Delivery:

• Cryo-recovery using in-house SOPF facilities • Worldwide delivery by professional breeders

Specifications

Expression driver gene:
Myh7
Target system:
Heart, muscle
Genetic background:
C57BL/6N
Cre type:
Inducible CreERT2
Reporter:
EGFP
Induction method:
Tamoxifen administration
MGI ID:
MGI:6122678

Scientific relevance & applications  

MYH7 encodes myosin heavy chain 7, a contractile protein predominantly expressed in cardiac muscle and slow-twitch skeletal muscle fibers. It is essential for heart function and muscle contraction. The Myh7-CreERT2 mouse line enables inducible, temporal control of genetic recombination in Myh7-expressing cells following tamoxifen administration. This model is particularly suited for studying cardiac biology, muscle physiology, and cardiovascular diseases.

Myh7-CreERT2 mouse line

mouse line

Get in touch about

Let us know how we can help
Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe