Nr5a1-CreERT2 mouse line

Inducible Cre driver for steroidogenic Nr5a1-expressing cells

Availability & Delivery:

• Cryo-recovery using in-house SOPF facilities • Worldwide delivery by professional breeders

Specifications

Expression driver gene:
Nr5a1
Target system:
Endocrine system, reproductive organs, adrenal gland
Genetic background:
C57BL/6N
Cre type:
Inducible CreERT2
Reporter:
EGFP
Induction method:
Tamoxifen administration
MGI ID:
MGI:6122674

Scientific relevance & applications  

NR5A1 (also known as SF-1) is a nuclear receptor critical for the development and function of steroidogenic tissues, including adrenal glands and gonads. It regulates genes involved in steroid hormone biosynthesis and reproductive development. The Nr5a1-CreERT2 mouse line enables inducible, temporal control of genetic recombination in Nr5a1-expressing cells following tamoxifen administration. This model is widely used for studying endocrine development, steroidogenesis, and reproductive biology.

Nr5a1-CreERT2 mouse line

mouse line

Get in touch about

Let us know how we can help
Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe