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• Cryo-recovery using in-house SOPF facilities • Worldwide delivery by professional breeders
SLC12A3 encodes a sodium-chloride cotransporter primarily expressed in the distal convoluted tubule of the kidney, where it plays a key role in electrolyte balance and renal function. Its expression is highly specific to renal tubular cells involved in ion transport. The Slc12a3-CreERT2 mouse line enables inducible, temporal control of genetic recombination in Slc12a3-expressing renal tubular cells following tamoxifen administration. This model is suitable for studying kidney physiology, electrolyte homeostasis, and renal disease mechanisms.
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