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SNHG11 is a long non-coding RNA with enriched expression in neuronal populations of the central nervous system. Its expression is associated with transcriptional regulation in brain tissues and may vary depending on developmental stage and cellular state. The Snhg11-CreERT2 mouse line enables inducible, temporal control of genetic recombination in Snhg11-expressing neuronal cells following tamoxifen administration. This model is suitable for conditional gene function studies, lineage tracing, and cell-state-specific genetic manipulation in neuroscience research, particularly in contexts where dynamic gene expression patterns are of interest.
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