Snhg11-CreERT2 mouse line

Inducible Cre driver for neuronal Snhg11-expressing cells

Availability & Delivery:

• Cryo-recovery using in-house SOPF facilities • Worldwide delivery by professional breeders

Specifications

Expression driver gene:
Snhg11
Target system:
Nervous system
Genetic background:
C57BL/6N
Cre type:
Inducible CreERT2
Reporter:
EGFP
Induction method:
Tamoxifen administration
MGI ID:
MGI:5659651

Scientific relevance & applications  

SNHG11 is a long non-coding RNA with enriched expression in neuronal populations of the central nervous system. Its expression is associated with transcriptional regulation in brain tissues and may vary depending on developmental stage and cellular state. The Snhg11-CreERT2 mouse line enables inducible, temporal control of genetic recombination in Snhg11-expressing neuronal cells following tamoxifen administration. This model is suitable for conditional gene function studies, lineage tracing, and cell-state-specific genetic manipulation in neuroscience research, particularly in contexts where dynamic gene expression patterns are of interest.

Snhg11-CreERT2 mouse line

mouse line

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