Syce1-CreERT2 mouse line

Inducible Cre driver for germ cell-specific Syce1-expressing cells

Availability & Delivery:

• Cryo-recovery using in-house SOPF facilities • Worldwide delivery by professional breeders

Specifications

Expression driver gene:
Syce1
Target system:
Reproductive system, germ cells
Genetic background:
C57BL/6N
Cre type:
Inducible CreERT2
Reporter:
EGFP
Induction method:
Tamoxifen administration
MGI ID:
MGI:6122676

Scientific relevance & applications  

SYCE1 encodes a component of the synaptonemal complex essential for meiotic chromosome synapsis in germ cells. It is specifically expressed during meiosis in oocytes and spermatocytes and is critical for fertility. The Syce1-CreERT2 mouse line enables inducible, temporal control of genetic recombination in Syce1-expressing germ cells following tamoxifen administration. This model is particularly suited for studying meiosis, germ cell development, and reproductive biology.

Syce1-CreERT2 mouse line

mouse line

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