T-cell engager development: the role of hCD3 models in safety and efficacy assessment

Content

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▶️ CD3xTAA bispecific antibodies induce anti-tumor response in both genO-hCD3ε and genO-panhCD3 mice

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▶️ genO-hCD3ε and genO-panhCD3 mice are suitable for studies in an auto-immunity context

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▶️ genO-panhCD3 mouse model can be used to assess T-cell engager-mediated cytokine release and associated clinical signs

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Speaker

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Fabiane Sônego, PhD in Immunology and Pharmacology, is the Director of Preclinical Models and Services at genOway. She has extensive expertise in in vivo models for immuno-oncology and inflammation and a proven track record of supporting researchers in advancing translational research and accelerating drug development.

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