Abcd4 conditional Knockout mouse

Target

Gene symbol :

Abcd4

NCBI gene ID :

19300

Gene full name :

ATP-binding cassette sub-family D member 4

Synonym :

ALDP2, Adrenoleukodystrophy protein-like 2

Protein function

Protein name :

ABCD4

Transports vitamin B₁₂ across lysosomal membranes

Expected phenotype

Impaired B₁₂ metabolism

Human disease relevance

Mutations cause methylmalonic aciduria and homocystinuria

Model applications

Lysosomal transport, metabolism

Keywords:

ABC transporter, Lysosome, B₁₂ metabolism

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Abcd4

conditional Knockout mouse

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