Abcd4 conditional Knockout mouse

Target

Gene symbol :

Abcd4

NCBI gene ID :

19300

Gene full name :

ATP-binding cassette sub-family D member 4

Synonym :

ALDP2, Adrenoleukodystrophy protein-like 2

Protein function

Protein name :

ABCD4

Transports vitamin B₁₂ across lysosomal membranes

Expected phenotype

Impaired B₁₂ metabolism

Human disease relevance

Mutations cause methylmalonic aciduria and homocystinuria

Model applications

Lysosomal transport, metabolism

Keywords:

ABC transporter, Lysosome, B₁₂ metabolism

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Abcd4

conditional Knockout mouse

Get in touch about

Let us know how we can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe