Abce1 conditional Knockout mouse

Target

Gene symbol :

Abce1

NCBI gene ID :

24015

Gene full name :

ATP-binding cassette, sub-family E member 1

Synonym :

RNase L inhibitor (RLI), OABP

Protein function

Protein name :

ABCE1

Inhibits RNase L and supports ribosome recycling; essential for translation and innate immunity

Expected phenotype

Embryonic lethality, impaired translation

Human disease relevance

Impacts viral resistance and neurological disorders

Model applications

Translation and antiviral response models

Keywords:

Ribosome recycling, RNase L, Translation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Abce1

conditional Knockout mouse

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