Acan conditional Knockout mouse

Target

Gene symbol :

Acan

NCBI gene ID :

11595

Gene full name :

Aggrecan

Synonym :

CSPG1, AGC1

Protein function

Protein name :

Aggrecan

Major component of cartilage ECM providing compressive resistance.

Expected phenotype

Skeletal and cartilage defects

Human disease relevance

Mutations cause skeletal dysplasia and joint diseases

Model applications

Skeletal development, osteoarthritis

Keywords:

Cartilage, ECM, Skeletal dysplasia

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Acan

conditional Knockout mouse

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