Acer1 conditional Knockout mouse

Target

Gene symbol :

Acer1

NCBI gene ID :

171168

Gene full name :

Alkaline ceramidase 1

Synonym :

—

Protein function

Protein name :

Alkaline ceramidase type 1

Hydrolyzes ceramides to sphingosine; regulates skin barrier and apoptosis

Expected phenotype

Knockouts show skin barrier defects and altered epidermal differentiation

Human disease relevance

Implicated in skin diseases and apoptosis regulation

Model applications

Studied in lipid signaling and skin homeostasis

Keywords:

Ceramide metabolism, Apoptosis, Skin biology, Sphingolipid

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Acer1

conditional Knockout mouse

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