Actn4 conditional Knockout mouse

Target

Gene symbol :

Actn4

NCBI gene ID :

60595

Gene full name :

Actinin alpha 4

Synonym :

α-Actinin-4, ACTN4

Protein function

Protein name :

ACTN4

Actin-binding protein for cytoskeletal cross-linking; involved in cell motility

Expected phenotype

Kidney disease, cytoskeletal defects

Human disease relevance

Mutations cause focal segmental glomerulosclerosis and proteinuria

Model applications

Cytoskeleton and renal disease models

Keywords:

Actin-binding, Cytoskeleton, Kidney disease

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Actn4

conditional Knockout mouse

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