Adam17 conditional Knockout mouse

Target

Gene symbol :

Adam17

NCBI gene ID :

11491

Gene full name :

ADAM metallopeptidase domain 17

Synonym :

TACE, CD156b

Protein function

Protein name :

ADAM17

Cleaves membrane-bound cytokines and receptors; regulates inflammation and development.

Expected phenotype

Developmental defects, immune dysfunction

Human disease relevance

Target in inflammatory diseases and cancer

Model applications

TNF signaling, shedding enzymes, inflammation

Keywords:

Sheddase, Metalloprotease, Cytokines

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Adam17

conditional Knockout mouse

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