Target

Gene symbol :  
Adap1
NCBI gene ID :  
231821
Gene full name :  
ArfGAP with dual PH domains 1
Synonym :  
Centaurin-α1

Protein function

Protein name :  
ArfGAP with dual PH domains 1
GTPase-activating protein involved in actin remodeling and membrane trafficking

Expected phenotype

KO affects neuronal morphology and migration

Human disease relevance

Implicated in neuronal development and synaptic plasticity

Model applications

Used in studies of ARF signaling and neuronal structure

Keywords:

ARF GTPase, Membrane trafficking, Neuronal migration, Actin

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Adap1

conditional Knockout mouse

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