Adap2 conditional Knockout mouse

Target

Gene symbol :

Adap2

NCBI gene ID :

216991

Gene full name :

ArfGAP with dual PH domains 2

Synonym :

Centaurin-delta2

Protein function

Protein name :

ArfGAP with dual PH domains 2

GTPase-activating protein for ARF6; involved in endothelial signaling and vesicle trafficking

Expected phenotype

KO mice show vascular abnormalities

Human disease relevance

Involved in cardiovascular disease and immune signaling

Model applications

Studied in endothelial cell biology and ARF signaling

Keywords:

GTPase-activator, ARF6, Vesicle trafficking, Vascular biology

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Adap2

conditional Knockout mouse

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