Target

Gene symbol :  
Adipor2
NCBI gene ID :  
68465
Gene full name :  
Adiponectin receptor 2
Synonym :  
PAMP-R2, AdipoR2

Protein function

Protein name :  
Adiponectin receptor protein 2
Receptor for adiponectin; regulates glucose and lipid metabolism via AMPK and PPAR-α pathways

Expected phenotype

Altered insulin sensitivity, increased inflammation, impaired lipid metabolism

Human disease relevance

Associated with type 2 diabetes, obesity, and metabolic syndrome

Model applications

Used in models of insulin resistance, obesity, and liver steatosis

Keywords:

Metabolism, Obesity, Diabetes, Adiponectin signaling

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Adipor2

conditional Knockout mouse

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