Target

Gene symbol :  
Aff3
NCBI gene ID :  
16764
Gene full name :  
AF4/FMR2 family member 3
Synonym :  
LAF4

Protein function

Protein name :  
AFF3
Transcriptional activator involved in lymphoid development and gene regulation.

Expected phenotype

Altered lymphoid cell function and gene expression.

Human disease relevance

Associated with leukemia and autoimmune diseases.

Model applications

Research on transcriptional regulation and lymphoid development.

Keywords:

Transcription factor, Lymphoid development, Autoimmunity

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Aff3

conditional Knockout mouse

Get in touch about

Let us know how can help
Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe