Akt1s1 conditional Knockout mouse

Target

Gene symbol :

Akt1s1

NCBI gene ID :

67605

Gene full name :

AKT1 substrate 1 (proline-rich)

Synonym :

PRAS40, 1700031F05Rik

Protein function

Protein name :

Proline-rich AKT1 substrate 1

Regulates mTORC1 signaling and insulin sensitivity

Expected phenotype

Altered mTOR signaling, metabolic disturbances

Human disease relevance

Implicated in cancer, insulin resistance

Model applications

Cancer metabolism, mTOR studies

Keywords:

mTOR, Insulin, Cell growth

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Akt1s1

conditional Knockout mouse

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