Target

Gene symbol :  
Aldh1b1
NCBI gene ID :  
72535
Gene full name :  
Aldehyde dehydrogenase 1 family, member B1
Synonym :  
Aldh5

Protein function

Protein name :  
Mitochondrial aldehyde dehydrogenase 1B1
Oxidizes acetaldehyde and other aldehydes in mitochondrial metabolism

Expected phenotype

Knockout affects pancreas development and mitochondrial redox balance

Human disease relevance

Implicated in type 2 diabetes and pancreatic cancer susceptibility

Model applications

Studied in metabolism, pancreatic development, and detoxification

Keywords:

Mitochondria, Aldehyde metabolism, Pancreas, Redox

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Aldh1b1

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe