Alkbh1 conditional Knockout mouse

Target

Gene symbol :

Alkbh1

NCBI gene ID :

211064

Gene full name :

AlkB homolog 1, histone H2A dioxygenase

Synonym :

ABH1

Protein function

Protein name :

Histone H2A dioxygenase ALKBH1

Involved in DNA demethylation and histone modification; regulates gene expression and development

Expected phenotype

Knockouts display growth retardation, neural tube defects, and epigenetic dysregulation

Human disease relevance

Implicated in cancer, epigenetic reprogramming, and infertility

Model applications

Used in studies of DNA repair, epigenetics, and embryogenesis

Keywords:

DNA demethylation, Histone modification, Epigenetics, Neural tube

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Alkbh1

conditional Knockout mouse

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