Target

Gene symbol :  
Alkbh8
NCBI gene ID :  
67667
Gene full name :  
AlkB homolog 8, tRNA methyltransferase
Synonym :  
ABH8, R08E3.4, AlkB homolog 8

Protein function

Protein name :  
AlkB homolog 8
Catalyzes methylation of tRNA; involved in RNA modification and stress response

Expected phenotype

Altered translational fidelity and response to stress

Human disease relevance

Linked to liver and kidney disorders

Model applications

RNA modification, stress biology

Keywords:

tRNA methylation, Oxidative stress

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Alkbh8

conditional Knockout mouse

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