Alox12e conditional Knockout mouse

Target

Gene symbol :

Alox12e

NCBI gene ID :

11685

Gene full name :

Arachidonate 12-lipoxygenase, epidermal type

Synonym :

12e-lipoxygenase

Protein function

Protein name :

ALOX12E

Produces 12-hydroxyeicosatetraenoic acid (12-HETE) involved in skin barrier function.

Expected phenotype

Abnormal skin barrier, lipid signaling changes

Human disease relevance

Implicated in ichthyosis and skin inflammation

Model applications

Skin biology, lipid metabolism

Keywords:

Lipoxygenase, Eicosanoids, Epidermis

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Alox12e

conditional Knockout mouse

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