Target

Gene symbol :  
Anapc4
NCBI gene ID :  
52206
Gene full name :  
Anaphase-promoting complex subunit 4
Synonym :  
CDC27-C, CDH1-associated protein

Protein function

Protein name :  
ANAPC4
Core subunit of APC/C E3 ubiquitin ligase complex; regulates mitotic progression

Expected phenotype

Mitotic arrest, developmental defects

Human disease relevance

Implicated in cell cycle disorders and cancer

Model applications

Cell division and cancer biology models

Keywords:

APC/C, Cell cycle, Ubiquitination

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Anapc4

conditional Knockout mouse

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