Target

Gene symbol :  
Aoc1
NCBI gene ID :  
76507
Gene full name :  
Amine oxidase, copper containing 1
Synonym :  
Abp1, Dao1

Protein function

Protein name :  
Diamine oxidase
Catalyzes oxidative deamination of histamine and polyamines

Expected phenotype

Knockouts show reduced histamine degradation

Human disease relevance

Implicated in histamine intolerance and inflammatory responses

Model applications

Used in studies of histamine metabolism and allergy

Keywords:

Histamine, Diamine oxidase, Polyamine, Inflammation

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Aoc1

conditional Knockout mouse

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