Arhgap26 conditional Knockout mouse

Target

Gene symbol :

Arhgap26

NCBI gene ID :

71302

Gene full name :

Rho GTPase activating protein 26

Synonym :

GRAF1, Graf

Protein function

Protein name :

Rho GTPase-activating protein 26

Regulates actin cytoskeleton remodeling via RhoA inactivation; involved in endocytosis

Expected phenotype

Knockout shows defects in synaptic vesicle recycling and T-cell function

Human disease relevance

Implicated in myelodysplastic syndromes and cancer

Model applications

Used in immune cell signaling, endocytosis, and cancer research

Keywords:

RhoGAP, Actin cytoskeleton, Endocytosis, T cells

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Arhgap26

conditional Knockout mouse

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